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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 781-790 of 2194 for surgery

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  1. International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

  2. A Study to Assess the Effectiveness, Safety, and Drug/Body Interactions of Rovalpituzumab for Third-Line and Later Treatment of Patients with Small Cell Lung Cancer that has Returned or is Resistant to Treatment

    Rochester, MN

  3. Hamstring Strain in High School Athletes

    Rochester, MN, Minneapolis, MN

  4. A Study of Afatinib Treatment for Patients with Epidermal Growth Factor Receptor Mutation Positive Non-Small Cell Lung Cancer, Who Are Age 70 or Older

    Scottsdale/Phoenix, AZ

  5. CREST: Capsular Repair During Hip Arthroscopy

    Scottsdale/Phoenix, AZ, Rochester, MN

  6. A Study to Evaluate Intralesional Injection of Triamcinolone Acetonide to Treat Desmoid Tumors

  7. A Study to Establish an Eclipse Continence System Registry

    Jacksonville, FL

  8. A Study of the FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study

    Rochester, MN

  9. Fluid Volume During Fluid Shifts

    Rochester, MN

  10. Studies on the Health Benefits of Pulsed Electromagnetic Field Therapy using Bioboosti

    Scottsdale/Phoenix, AZ

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