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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 771-780 of 2194 for surgery

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  1. International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

  2. A Study to Assess the Effectiveness, Safety, and Drug/Body Interactions of Rovalpituzumab for Third-Line and Later Treatment of Patients with Small Cell Lung Cancer that has Returned or is Resistant to Treatment

    Rochester, MN

  3. Hamstring Strain in High School Athletes

    Rochester, MN, Minneapolis, MN

  4. A Study of Afatinib Treatment for Patients with Epidermal Growth Factor Receptor Mutation Positive Non-Small Cell Lung Cancer, Who Are Age 70 or Older

    Scottsdale/Phoenix, AZ

  5. CREST: Capsular Repair During Hip Arthroscopy

    Scottsdale/Phoenix, AZ, Rochester, MN

  6. A Study to Evaluate Intralesional Injection of Triamcinolone Acetonide to Treat Desmoid Tumors

  7. A Study of the Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction

    Rochester, MN

  8. A Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Participants With Extensive Stage Small Cell Lung Cancer (MERU)

    Rochester, MN

  9. The Effect of Spatz3 Adjustable Balloon System Plus Diet and Exercise on Gastric Electrical Activity and Emptying

    Rochester, MN

  10. Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEER

    Scottsdale/Phoenix, AZ

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