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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study of the Safety and Effectiveness of Home Monitoring of Blood Clotting Factors in Adults with Congenital Heart Disease

    Rochester, MN

  2. A Study to Evaluate the Long-Term Safety and Effectiveness of Ubenimex in Patients with Pulmonary Arterial Hypertension

    Rochester, MN

  3. A Study to Determine the Effects of Cardiac Resynchronization Therapy on Blood Vessel Tissue and Heart Function for Patients with Heart Failure

    Rochester, MN

  4. The Relationship Between Age and Carpal Tunnel Size

    Jacksonville, FL

  5. A Phase 2, Multicenter, Randomized Study of AP26113

    Rochester, MN

  6. Epsilon Aminocaproic Acid (EACA) for the Reduction of Blood Loss in Total Hip Arthroplasty (THA)

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  7. Atezolizumab Immunotherapy in Patients With Advanced NSCLC (AJCC 7th Edition)

  8. A Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Participants With Extensive Stage Small Cell Lung Cancer (MERU)

    Rochester, MN

  9. The Effect of Spatz3 Adjustable Balloon System Plus Diet and Exercise on Gastric Electrical Activity and Emptying

    Rochester, MN

  10. A Study Comparing X-396 (Ensartinib) to Crizotinib in Patients with ALK Positive Non-Small Cell Lung Cancer

    Scottsdale/Phoenix, AZ

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