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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 751-760 of 2194 for surgery

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  1. Atezolizumab Immunotherapy in Patients With Advanced NSCLC (AJCC 7th Edition)

  2. Cardiovascular Effects of Energy Drinks in Healthy Adults

    Rochester, MN

  3. A Study to Assess the Effectiveness and Safety of Rilonacept Treatment in Subjects with Recurrent Pericarditis

    Rochester, MN

  4. A Study of the Effectiveness and Safety of Rivaroxaban on Venous Thromboembolic Risk in Patients Following Hospital Discharge

  5. A Study for Sources of Pulmonary Congestion Associated with Heart Failure

    Rochester, MN

  6. A study to assess the safety and efficacy of MANP, a new blood pressure lowering mediation in African Americans with high blood pressure.

    Rochester, MN

  7. Saline-Enhanced Radiofrequency Catheter Ablation for the Treatment of Ventricular Tachycardia

  8. A Study to Understand the Physical Characteristics of Healthy and Diseased Artery Walls

    Rochester, MN

  9. A Study of the Long-Term Safety of Tafamidis for Patients with Transthyretin Cardiomyopathy

    Rochester, MN

  10. A Study Comparing X-396 (Ensartinib) to Crizotinib in Patients with ALK Positive Non-Small Cell Lung Cancer

    Scottsdale/Phoenix, AZ

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