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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 651-660 of 2188 for surgery

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  1. A Study Comparing Carotid Revascularization Endarterectomy Versus Stenting

    Jacksonville, FL

  2. A Dose-response of the Effects of Exendin-9,39 on GI Symptoms and Food Intake

    Rochester, MN

  3. Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure

    Rochester, MN

  4. Extending Preservation and Assessment Time of Donor Lungs Using the Toronto EVLP System™ at a Dedicated EVLP Facility

  5. Safety of BM-MNC Intramyocardial Delivery in Ebstein RV

    Rochester, MN

  6. Use of Intra-Operative Shear Wave Ultrasound Vibrometry for Characterization of Esophageal Malignant Tumors

    Rochester, MN

  7. A Study to Evaluate the Clinical Utility for the Ion™ Endoluminal System

    Rochester, MN

  8. Outcomes of Meniscus Root Repair Using a Transtibial Pullout Technique

    Rochester, MN

  9. Implantation of the HiRes90K™ Advantage Cochlear Implant With HiFocus™ Mid-Scala and Development of a Combined Electric and Acoustic Stimulation Technology in Adults with Partial Deafness

    Rochester, MN

  10. Survivorship of Attune Primary Total Knee Prosthesis

    Scottsdale/Phoenix, AZ

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