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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study Evaluating the Safety and Effectiveness of the PulseRider® Aneurysm Neck Reconstruction Device Used in Conjunction With Endovascular Coil Embolization in the Treatment of Wide-Neck Bifurcation Intracranial Aneurysm

    Rochester, MN

  2. Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT)

    Rochester, MN

  3. Terlipressin for HRS-AKI in Liver Transplant Candidates (INFUSE) (INFUSE)

    Rochester, MN

  4. A Dose-response of the Effects of Exendin-9,39 on GI Symptoms and Food Intake

    Rochester, MN

  5. Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure

    Rochester, MN

  6. Extending Preservation and Assessment Time of Donor Lungs Using the Toronto EVLP System™ at a Dedicated EVLP Facility

  7. Feasibility Testing of the Alert for Atrial Fibrillation Program

    Rochester, MN

  8. A Study to Analyze if Exercise Echocardiography Can Identify Ventricular and Vascular Function Abnormalities That are Undetectable at Rest for Patients With Coarctation of Aorta (COA)

    Rochester, MN

  9. A Study to Evaluate Feasibility of Fractional CO2 Vaginal LASER Therapy for Recurrent Urinary Tract Infection

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  10. A Study Comparing Sublobar Resection versus Stereotactic Ablative Radiotherapy for Lung Cancer

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