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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1061-1070 of 2189 for surgery

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  1. Supporting Patients Undergoing HIgh-Risk PCI Using a High-Flow PErcutaneous Left Ventricular Support Device

    Rochester, MN

  2. MARK 1A Series: Percutaneous Microwave Ablation for Patients With Lung Tumor(s)

  3. A Study to Evaluate the Utility of Focused Frailty Interventions on Patients with Advanced Heart Failure

    Rochester, MN

  4. Use of Cardiac Magnetic Resonance Imaging (cMRI) and Echocardiogram to Diagnose Constrictive Pericarditis and Restrictive Cardiomyopathy

    Rochester, MN

  5. An Evaluation of the MitraClip System for treatment of Mitral Regurgitation in Heart Failure Patients

    Scottsdale/Phoenix, AZ

  6. A Study to Evaluate AuTophagy Activation for Cardiomyopathy Due to Anthracycline tReatment

    Rochester, MN

  7. Connected Health Care in Exercise Program for Obesity

    Scottsdale/Phoenix, AZ

  8. Study of the Safety, Pharmacokinetics and Efficacy of EDO-S101, in Patients With Advanced Solid Tumors

  9. A Study of Paclitaxel with or without Cixutumumab as Second-Line Therapy for Treating Patients with Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. A Study to Find the Recommended Dose for Further Research for VX-970 and Whole Brain Radiation Therapy to Treat Patients with Brain Metastases from Non-Small Cell Lung Cancer

    Jacksonville, FL, Rochester, MN

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