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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 96 for spine

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  1. Dorsal spinal cord stimulation vs medical management for the treatment of low back pain

    Rochester, MN

  2. Investigation of Neurocognitive Measures of Sport-Related Injury

    Rochester, MN

  3. A Study to Evaluate Patient Experience Comparing Tonic vs. Burst Spinal Card Stimulation for Chronic Pain

    Jacksonville, FL

  4. A Study of Transcutaneous and Epidural Spinal Stimulation for Enabling Motor Function in Humans with Motor Complete Paraplegia

    Rochester, MN

  5. A Study Using Spinal Stimulation During Exercise in Patients with Heart Failure

    Rochester, MN

  6. Study of BN Brachyury and Radiation in Advanced Chordoma Patients

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  7. Shared Decision Making in Patients with Neck and Back Pain – Options in Neck and Back Pain Management

    Rochester, MN

  8. Phase I Clinical Trial of Autologous Adipose Derived Mesenchymal Stem Cells in the Treatment of Paralysis due to Traumatic Spinal Cord Injury

    Rochester, MN

  9. A Study to Compare HF10 Therapy Combined With CMM to CMM Alone in the Treatment of Non-Surgical Refractory Back Pain

    Scottsdale/Phoenix, AZ

  10. Performance and Nutrition Program for Athletes in Adaptive Sports

    Rochester, MN

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