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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 96 for spine

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  1. A Study to Evaluate the Safety and Effectiveness of the Spineology Interbody Fusion System in Lumbar Fusion Procedures

    Rochester, MN

  2. Transforaminal Lumbar Interbody Fusion (TLIF)

    Rochester, MN

  3. Efficacy of Riluzole in Surgical Treatment for Cervical Spondylotic Myelopathy (CSM-Protect)

    Rochester, MN

  4. Spinal Cord Injury Epidural Stimulation

    Rochester, MN

  5. A Study to Evaluate Autologous Adipose Derived Mesenchymal Stem Cells to Treat Spinal Cord Injury Patients

    Rochester, MN

  6. A Study to Evaluate Anterior Vertebral Body Tethering (AVBT) Zimmer Biomet Tether System or Dynesys System to Treat Pediatric Scoliosis

    Rochester, MN, Minneapolis, MN, Eau Claire, WI, La Crosse, WI

  7. Sleep Apnea After Anterior Cervical Discectomy and Fusion

    Jacksonville, FL

  8. Riluzole in Spinal Cord Injury Study

    Rochester, MN

  9. Study Evaluating the Side Effects of Bone Marrow-Derived Stem Cells When Injected Into the Facet Joints for the Treatment of Painful Arthropathies

    Jacksonville, FL

  10. Spinal Stimulation to Treat Low Back Pain

    Rochester, MN

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