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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 87 for spine

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  1. MIMO Clinical Trial

    Rochester, MN

  2. A Study of the Effect of Treatment on Activity and Muscle Function in Pediatric Patients with Scoliosis

    Rochester, MN

  3. A Study to Determine the Value of Combining PET and MRI Evaluations of Spinal Joint Pain in the Lower Back

    Rochester, MN

  4. A Study to Assess Vertebral Fracture Risk using Vertebral Fracture Assessment and Vertebral Strength Assessment with Dual Energy X-ray Absorptiometry (DXA-Finite Element Analysis) in Liver Transplant Recipients during Pre-transplant Period

    Jacksonville, FL

  5. Study of BN Brachyury and Radiation in Advanced Chordoma Patients

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. Efficacy of Riluzole in Surgical Treatment for Cervical Spondylotic Myelopathy (CSM-Protect)

    Rochester, MN

  7. Sleep Apnea After Anterior Cervical Discectomy and Fusion

    Jacksonville, FL

  8. Spinal Cord Injury Epidural Stimulation

    Rochester, MN

  9. SI Joint Stabilization in Long Fusion to the Pelvis

    Rochester, MN

  10. Investigation of Neurocognitive Measures of Sport-Related Injury

    Rochester, MN

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