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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 96 for spine

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  1. A Study of Platelet Rich Plasma for the Treatment of Degenerative Joint Disease of the Lumbar Spine

    Rochester, MN

  2. MIMO Clinical Trial

    Rochester, MN

  3. A Study of Muscle Activation of Shoulder Complex and Spine Stabilizers during the Standard Push-up and Pushing Exercises using a Suspension Strap Training System

    Rochester, MN

  4. Evaluation of t-RFA and RF-TVA Prior to/Following Radiation Therapy to Treat Painful Metastatic Vertebral Body Tumor(s)

    Rochester, MN

  5. A Study of the Effect of Treatment on Activity and Muscle Function in Pediatric Patients with Scoliosis

    Rochester, MN

  6. Transforaminal Lumbar Interbody Fusion (TLIF)

    Scottsdale/Phoenix, AZ

  7. A Study to Determine the Value of Combining PET and MRI Evaluations of Spinal Joint Pain in the Lower Back

    Rochester, MN

  8. Posterior Fossa Decompression with or without Duraplasty for Chiari Type I Malformation with Syringomyelia

    Rochester, MN

  9. SI Joint Stabilization in Long Fusion to the Pelvis

    Rochester, MN

  10. A Study to Assess Vertebral Fracture Risk using Vertebral Fracture Assessment and Vertebral Strength Assessment with Dual Energy X-ray Absorptiometry (DXA-Finite Element Analysis) in Liver Transplant Recipients during Pre-transplant Period

    Jacksonville, FL

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