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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 33 for psychiatry and psychology

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  1. A Prospective Registry for Patients with REM Sleep Behavior Disorder and Polysomnographic REM Sleep without Atonia and Controls

    Rochester, MN

  2. A Study Evaluating the Prevalence, Incidence and Predictors for Development of the Impulse Control Disorders in Patients with Prolactinomas Treated with Dopamine Agonist Therapy

    Rochester, MN, Jacksonville, FL

  3. Pediatric Pain Rehabilitation Treatment Outcomes for Chronic Noncancer Pain

    Rochester, MN

  4. A Study to Analyse the Genetic Makeup of Those with Opioid and Substance Use Disorders

    Albert Lea, MN, Rochester, MN

  5. Magnetic Resonance Elastography of Dementia

    Rochester, MN

  6. A Study to Evaluate a Primary Care-Based Intervention for Adolescent Restrictive Eating Disorders

    Rochester, MN

  7. Patterns of Co-use of Nicotine and Cannabis Electronic Cigarettes, and Its Association with Perceived Social Support in Young Adults

    Eau Claire, WI

  8. ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

    Jacksonville, FL, Rochester, MN

  9. Advanced Care Planning in Dementia

    Jacksonville, FL

  10. Early Naturalistic Hands-on Autism Caregiver Training

    Rochester, MN

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