Thrombin Generation before and after Cardiopulmonary Bypass in Pediatric Patients


About this study

The goal of this study is to survey the intraoperative dynamics of thrombin generation in pediatric patients ≤ 20 kg undergoing cardiac surgery.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Consent to participate in the study.
  • Weight > 2.5 kg, ≤ 20 kg.
  • No preoperative therapeutic anticoagulation exposure or antithrombin replacement.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Elena Ashikhmina, M.D., Ph.D.

Closed for enrollment

More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

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