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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 75 for pain

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  1. A Study of the Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia

    Rochester, MN

  2. A Study to Evaluate the Safety and Effectiveness of Fremanezumab in Adult Migraine Patients

    Jacksonville, FL

  3. A Study to Analyze Surgical Outcomes and Predictors of Treatment for Hip Diseases

    Rochester, MN

  4. A Study to Evaluate the Effectiveness and Safety of Cannabidiol for Gastroparesis and Functional Dyspepsia

    Rochester, MN

  5. Laser Therapy for Survivors of Gynecological Cancer

    Rochester, MN

  6. Patient Satisfaction in Mohs Micrographic Surgery with Supplemental Lidocaine Jelly

    Scottsdale/Phoenix, AZ

  7. A Study of Preventive Treatment of Oxaliplatin Induced Peripheral Neuropathy in Metastatic Colorectal Cancer (POLAR-M)

    La Crosse, WI

  8. A Study to Evaluate Resting State Connectivity in Adolescents with Postural Orthostatic Tachycardia Syndrome and Chronic Pain

    Rochester, MN

  9. A Study to Evaluate Chest Pain Risk Stratification Using HEART Pathway in Community Emergency Departments

    Eau Claire, WI

  10. A Study to Evaluate Paraspinal Pain in Patients Undergoing Fenestrated-branched Endovascular Aortic Repair for Thoracoabdominal Aortic Aneurysms

    Rochester, MN

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