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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 74 for pain

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  1. A Study to Evaluate Prevention of Paclitaxel-Associated Neuropathy with Fingolimod

    Rochester, MN

  2. A Study of Quality of Life and Pain Control Before and After Endovascular Renal Denervation in Individuals with Refractory Kidney Pain

    Rochester, MN

  3. Exparel Injection for Postoperative Orbital Pain

    Rochester, MN

  4. A Study of Pain Control Following Sinus Surgery

    Rochester, MN

  5. A Study to Assess the Quinagolide Vaginal Ring for Endometriosis-related Pain

    Rochester, MN

  6. A Study to Evaluate the Effectiveness of Ganglion Block on Headache Pain Secondary to Aneurysmal Subarachnoid Hemorrhage

    Rochester, MN

  7. CREST: Capsular Repair During Hip Arthroscopy

    Scottsdale/Phoenix, AZ, Rochester, MN

  8. A Study to Evaluate Operative Versus Non-Operative Treatment for Atraumatic Rotator Cuff Tears

    Scottsdale/Phoenix, AZ

  9. Endpoint Determination Study Protocol

    Jacksonville, FL

  10. A Study to Evaluate the Therapeutic Effectiveness of Rifaximin in Diabetic Gastroparesis Patients Using Bloating as the Primary Endpoint

    Jacksonville, FL

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