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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 161-170 of 795 for cardiovascular

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  1. d68Ga-DOTATATE PET/CT Assessment of Cardiac Sarcoidosis

    Rochester, MN

  2. A Study To Evaluate The Use Of MANP In Patients With Hypertension And Metabolic Syndrome

    Rochester, MN

  3. Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT)

    Rochester, MN

  4. Continuous Data Collection and Analysis for Stroke Prevention Using a Wearable Sensor

    Rochester, MN

  5. A Study To Evaluate The Efficacy And Safety Of GDC-8264 In Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) And Major Adverse Kidney Events (MAKE)

    Rochester, MN

  6. A Study to Evaluate a Computerized Stethoscope called ©CompuSteth to Diagnose Heart Disease

    Rochester, MN

  7. Efficacy Of Delayed Enhancement MRI-Guided Ablation Vs Conventional Catheter Ablation Of Atrial Fibrillation

    Rochester, MN

  8. Outcomes of Advanced Practice Providers Focused Cardiac Ultrasound Training

  9. Peripheral Nerve Stimulation Therapy For Atrial Fibrillation

    Rochester, MN

  10. A Study To Evaluate AuTophagy Activation For Cardiomyopathy Due To Anthracycline TReatment

    Rochester, MN

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