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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 51-60 of 703 for cancer

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  1. A Study to Evaluate the Safety and Therapeutic Activity of GI-102 in Patients With Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. PRE-I-SPY Phase I/Ib Oncology Platform Program

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. A Comparison of TULSA Procedure vs. Radical Prostatectomy in Participants With Localized Prostate Cancer (CAPTAIN)

    Rochester, MN, Jacksonville, FL

  4. I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer (I-SPY)

    Rochester, MN

  5. Empty Bladder Impact During Radiation Therapy for Prostate Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Albert Lea, MN, Eau Claire, WI, La Crosse, WI, Mankato, MN, Rochester, MN

  6. A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Patients With Advanced Solid Tumors

    Jacksonville, FL, Rochester, MN

  7. A Phase 1/2a Study of IMM-1-104 in Participants With Previously Treated, RAS-Mutant, Advanced or Metastatic Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  8. Comparison of standard care with radiation and medicinal therapy vs radiation alone for prostate cancer

    Rochester, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL

  9. (Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. ALPN-202 With PD-1 Inhibition in Advanced Malignancies

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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