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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 61-70 of 703 for cancer

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  1. Monitoring Neoadjuvant Chemotherapy of Breast Cancer Using 3D Subharmonic Aided Pressure Estimation

    Rochester, MN

  2. Minority-inclusive Imaging Biomarker-based End of Therapy Trial for 177Lu-PSMA-617

    Rochester, MN

  3. Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. Dual BET and CBP/p300 Inhibitor in Patients With Targeted Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors (SPX-303)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. Chemotherapy Combined With Immunotherapy vs Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

    Eau Claire, WI, Mankato, MN

  8. Comparison of standard care with radiation and medicinal therapy vs radiation alone for prostate cancer

    Rochester, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL

  9. Pre-Op / Post-Op Hypofractionation Radiotherapy in Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  10. (Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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