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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 701 for cancer

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  • Study status: Open/Status Unknown
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  1. A First-in-Human Study of BG-C137, an Anti-FGFR2b Antibody Drug Conjugate, in Participants With Advanced Solid Tumors

    Rochester, MN

  2. Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302)

    Scottsdale/Phoenix, AZ, Rochester, MN

  3. Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Patients With Metastatic Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. Acceptance and Commitment Therapy Compassion-Based Virtual Group Intervention for Diverse Cancer Patients

    Scottsdale/Phoenix, AZ

  5. CJNJ-67652000 and Prednisone for the Treatment of Men With Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations

    Jacksonville, FL, Rochester, MN, Scottsdale/Phoenix, AZ

  6. Empty Bladder Impact During Radiation Therapy for Prostate Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Albert Lea, MN, Eau Claire, WI, La Crosse, WI, Mankato, MN, Rochester, MN

  7. Rapid-Plan Knowledge-Based Planning vs. Human-Driven Planning for Prostate Cancer Radiotherapy

    Scottsdale/Phoenix, AZ

  8. INCB161734 for Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

    Scottsdale/Phoenix, AZ

  9. Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers

    Rochester, MN

  10. Study of RP-6306 Alone or in Combination With RP-3500 in Patients With Advanced Solid Tumors

    Jacksonville, FL, Rochester, MN

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