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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 834 for cancer

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  1. A Study to Evaluate Whether Probiotics for Gut Microbiome Will Target Cancer Immune Microenvironment in Breast and Lung Cancer

    Jacksonville, FL

  2. Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score

    Albert Lea, MN

  3. ALPN-202 With PD-1 Inhibition in Advanced Malignancies

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. A Trial of ZL-1201 in Subjects with Advanced Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  5. A Study of AMG 757 in Participants With Neuroendocrine Prostate Cancer

    Scottsdale/Phoenix, AZ

  6. Niraparib + TSR042 In BRCA Mutated Breast Cancer

    Rochester, MN

  7. VSV-hIFNbeta-NIS in Treating Patients With Stage IV or Recurrent Endometrial Cancer

    Rochester, MN

  8. First in Human Study of TORL-1-23 in Participants With Advanced Cancer

    Rochester, MN

  9. A Study to Evaluate Neoadjuvant and Personalized Agents to Treat Breast Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN

  10. A Study to Develop Early Detection Test to Reduce Racial Disparities in Endometrial Cancer (EC) Mortality

    Jacksonville, FL

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