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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 111-120 of 456 for breast cancer

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  1. 3D Ultrasound Vascular Imaging for Breast Cancers

    Rochester, MN

  2. Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Patients With Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer

    Rochester, MN

  3. Randomized, Open Label, Clinical Study of the Targeted Therapy, Palbociclib, to Treat Metastatic Breast Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN

  4. Akt Inhibitor MK-2206 and Anastrozole With or Without Goserelin Acetate in Treating Patients With Stage II-III Breast Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN

  5. Breast Cancer, Reasoning, And Activity Intervention

    Scottsdale/Phoenix, AZ

  6. Z-Endoxifen Hydrochloride in Treating Patients with Metastatic or Locally Recurrent Estrogen Receptor-Positive Breast Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN

  7. Study to Compare Contrast-Enhanced Ultrasound, Contrast-Enhanced Dual Energy Mammography, and Contrast-Enhanced Breast MR for Early Breast Cancer Detection

  8. A Consortium Trial to Evaluate Proton vs. Photon Therapy for Patients with Non-metastatic Breast Cancer

    Jacksonville, FL

  9. Density MATTERS [Molecular Breast Imaging (MBI) And Tomosynthesis To Eliminate the Reservoir]

    Rochester, MN, La Crosse, WI

  10. A Study to Compare Elacestrant vs. Standard of Care for the Treatment of Patients with ER+/HER2- Advanced Breast Cancer

    Rochester, MN

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