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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 73 for Nephrology and Hypertension

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  • Study status: Open/Status Unknown
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  1. Cardiovascular Effects of Energy Drinks in Healthy Adults

    Rochester, MN

  2. Caloric Restriction in Autosomal Dominant Polycystic Kidney Disease

    Rochester, MN

  3. A Study to Evaluate Effectiveness of Preventing Urinary Stones With Hydration

    Rochester, MN

  4. A Study of Quality of Life and Pain Control Before and After Endovascular Renal Denervation in Individuals with Refractory Kidney Pain

    Rochester, MN

  5. A Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients

    Rochester, MN

  6. Cardiovascular Effects of Adderall in Healthy Young Adults

    Rochester, MN

  7. Study of Intravenous Sodium Thiosulfate in Acute Calciphylaxis Patients

    Jacksonville, FL

  8. A Study Comparing Standard Treatment versus Accelerated Initiation of Renal Replacement Therapy for Acute Kidney Injury

    Rochester, MN

  9. PRevention of Acute Kidney Injury Initiated with Electronic Surveillance Enhancement

    Rochester, MN

  10. A Study of Cemdisiran in Adults With Immunoglobulin A Nephropathy (IgAN)

    Rochester, MN

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