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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 69 for Nephrology and Hypertension

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  • Study status: Open/Status Unknown
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  1. Cardiovascular Effects of Adderall in Healthy Young Adults

    Rochester, MN

  2. Cardiovascular Effects of Energy Drinks in Healthy Adults

    Rochester, MN

  3. Caloric Restriction in Autosomal Dominant Polycystic Kidney Disease

    Rochester, MN

  4. A Study of Quality of Life and Pain Control Before and After Endovascular Renal Denervation in Individuals with Refractory Kidney Pain

    Rochester, MN

  5. A Study to Evaluate Effectiveness of Preventing Urinary Stones With Hydration

    Rochester, MN

  6. A Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients

    Rochester, MN

  7. Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR) in Adult Renal Transplant Recipients

    Scottsdale/Phoenix, AZ, Rochester, MN

  8. PRevention of Acute Kidney Injury Initiated with Electronic Surveillance Enhancement

    Rochester, MN

  9. A Study of Cemdisiran in Adults With Immunoglobulin A Nephropathy (IgAN)

    Rochester, MN

  10. Training of Physicians in Critical Care Ultrasonography (CCUS)

    Rochester, MN

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