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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 18 for Critical Care

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  • Study status: Open/Status Unknown
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  1. Training of Physicians in Critical Care Ultrasonography (CCUS)

    Rochester, MN

  2. Study of the Incidence of Electrographic Status Epilepticus and Seizures of PICU Patients at National Children’s Hospital in Hanoi, Vietnam.

    Rochester, MN

  3. A Study to Assess Steroid Dosing by bioMARker Guided Titration in Critically Ill Patients With Pneumonia

    Rochester, MN

  4. Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine

    Rochester, MN

  5. Study to Determine Safety and Effectiveness of Ascorbic Acid, Corticosteroids, and Thiamine in Treating Sepsis and Septic Shock

    Scottsdale/Phoenix, AZ

  6. A Study to Compare Non-invasive Near-infrared Spectroscopy (NIRS) to Invasive Licox Intracranial Pressure Monitoring in Neurocritical Care

    Rochester, MN

  7. Real Time Detection of Electrophysiologic Disturbances Following Subdural Hematoma Evacuation

    Rochester, MN

  8. COVID-19 Remote Monitoring

    Jacksonville, FL

  9. Study to Compare Electrical and Ultrasonographic Evaluation of the Phrenic Nerve-Diaphragm Neuromuscular Junction (NMJ) Function

    Jacksonville, FL

  10. A Study to Detect Non-convulsive Seizures with Single-channel Electroencephalogram (EEG)

    Rochester, MN

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