A Multimodal Monitoring (MMM) Computer to Detect Physiologic Trends in Data in Neurointensive Care Unit Patients


About this study

The purpose of this study is to identify important physiologic trends in bedside ICU data such as cerebral perfusion pressure (CPP), intracranial pressure (ICP) using a bedside “Multimodal monitoring” (MMM) computer which utilizes ICM+ Cambridge software.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  1. Admission to the Neuro ICU at MCF or MCR with diagnosis of brain-injured subjects who require intense vital sign monitoring in the ICU environment as standard of care.
  2. Males and females, aged 18 –90 years,
  3. Brain injury either from stroke (ischemic, subarachnoid hemorrhage, intraparenchymal, intraventricular, traumatic), or cerebral anoxia.

Exclusion Criteria: 

  1. Pregnant and/or breast-feeding females
  2. Institutionalized individuals

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

William Freeman, M.D.

Contact us for the latest status

Contact information:

William Freeman M.D.

(904) 953-6869


Jacksonville, Fla.

Mayo Clinic principal investigator

William Freeman, M.D.

Contact us for the latest status

More information


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