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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 71 for Urology

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  • Study status: Open/Status Unknown
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  1. Cisplatin and Gemcitabine Hydrochloride With or Without ATR Kinase Inhibitor VX-970 in Treating Patients With Metastatic Urothelial Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  2. Efficacy of Penile Traction Therapy Using a Novel Device

    Rochester, MN, Rochester, MN

  3. A Study to Evaluate INSTILADRIN® in Patients With High Grade, Bacillus Calmette-Guerin (BCG) Unresponsive NMIBC

    Rochester, MN

  4. A Study of APR-246 and Pembrolizumab in Patients with Solid Tumor Malignancies

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  5. Study to Evaluate 99mTc-MIP-1404 SPECT/CT Imaging in Men With Biopsy Proven Low-Grade Prostate Cancer

    Rochester, MN, Rochester, MN

  6. Hypo-fractionated Proton Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Prostate Cancer

    Scottsdale/Phoenix, AZ

  7. Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  8. International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)

    Rochester, MN

  9. Penile Length Restoration in Men with Type II Diabetes

    Rochester, MN

  10. A Phase 3 Randomized, Placebo-controlled, Double-blind Study of Niraparib in Combination with Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Subjects with Metastatic Prostate Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL

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