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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 71 for Urology

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  1. MR-Guided Cryoablation of Prostate Bed Recurrences

    Rochester, MN

  2. A Study to Test the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) with One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

    Eau Claire, WI, Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. A Study of Nivolumab or Nivolumab Plus Experimental Medication BMS-986205 With or Without Bacillus Calumette-Guerin (BCG) in BCG Unresponsive Bladder Cancer That Has Not Invaded Into the Muscle Wall of the Bladder

    Scottsdale/Phoenix, AZ

  4. A Study to Evaluate the Safety, Tolerability, Drug/Body Interactions, and Activity of Oradoxel for Patients with Advanced Malignancies

    Rochester, MN, Scottsdale/Phoenix, AZ

  5. A Study of Nab-Paclitaxel as Maintenance Treatment After Cisplatin-Based Chemotherapy and Surgery for Patients with High-Risk Bladder Cancer

    Scottsdale/Phoenix, AZ

  6. A Study of Rucaparib Verses Physician's Choice of Therapy in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. A Trial to Evaluate the Safety of GEN1046 in Patients with Malignant Solid Tumors

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  8. An Extension Study MRI/US Fusion Imaging and Biopsy in Combination With Nanoparticle Directed Focal Therapy for Ablation of Prostate Tissue

    Rochester, MN

  9. Retroperitoneal Lymph Node Dissection in Treating Patients With Stage I-IIA Testicular Seminoma

    Rochester, MN

  10. A Study to Evaluate Nutrition Therapy in Improving Immune System in Bladder Cancer Patients

    Jacksonville, FL, Rochester, MN

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