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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 266 for Gastroenterology and Hepatology

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  • Study status: Open/Status Unknown
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  1. Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

    Rochester, MN

  2. Endpoint Determination Study Protocol

    Jacksonville, FL

  3. A Safety Study of SEA-TGT in Patients With Advanced Cancer

    Rochester, MN

  4. A Study of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

    La Crosse, WI

  5. A Trial to Evaluate the Safety of GEN1046 in Patients with Malignant Solid Tumors

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  6. Whole-Food, Plant-Based Diet for Active Crohn’s Disease

    Rochester, MN

  7. A Study to Detect Minimally-Invasive Barrett's Esophagus and Barrett's Esophagus Related Dysplasia/Carcinoma

    Rochester, MN, Jacksonville, FL, Austin, MN, Scottsdale/Phoenix, AZ

  8. A Study to Evaluate the Safety, Tolerability, Drug/Body Interactions, and Activity of Oradoxel for Patients with Advanced Malignancies

    Rochester, MN, Scottsdale/Phoenix, AZ

  9. A Study to Evaluate the Safety and Effectiveness of Etrasimod in Adults with Eosinophilic Esophagitis

    Rochester, MN

  10. PCI Treatment/Gemcitabine & Chemotherapy vs Chemotherapy Alone in Patients With Inoperable Extrahepatic Bile Duct Cancer

    Rochester, MN

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