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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 266 for Gastroenterology and Hepatology

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate the Safety and Effectiveness of NX9 for CT Imaging in Patients with Cancer or GI Disease

    Rochester, MN

  2. A Study to Evaluate Niraparib and TSR-042 in Patients with Germline or Somatic BRCA1/2 and PALB2-related Pancreatic Cancer

    Rochester, MN, Jacksonville, FL, Scottsdale/Phoenix, AZ

  3. A Study of Colesevelam in Fecal Incontinence

    Rochester, MN

  4. UC Cohort - The Influence of Diet on Gut Microbiotas

    Rochester, MN

  5. A Study of MT-5111 in HER2-positive Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. A Study to Analyze Onvansertib Treatment in Patients with Metastatic Pancreatic Ductal Adenocarcinoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. Phase II Study of NGC-Triple Regimen in Potentially Resectable Pancreatic Cancer Patients

    Scottsdale/Phoenix, AZ, Rochester, MN

  8. Safety and Effectiveness of Esophageal Self Dilation for Benign Refractory Esophageal Stricture Management

    Scottsdale/Phoenix, AZ, Rochester, MN

  9. A Study to Evaluate the Effectiveness and Safety of Aramchol Versus Placebo in Subjects With NASH (ARMOR)

    Rochester, MN

  10. A Study of Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Patients With Crohn's Disease

    Jacksonville, FL

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