Andree H. Koop, M.D.

The purpose of this study is to determine if virtual reality (VR) will improve symptoms in non-cardiac chest pain (NCCP).

The purpose of this study is to assess the incidence of small intestinal bacterial overgrowth (SIBO) in patients with symptoms of gastroesophageal reflux disease treated with proton pump inhibitors.

The purpose of this study is to define normative values on HRM  in asymptomatic, elderly individuals ≥ to 65 years old.   We hypothesize that elderly persons will have a higher prevalence of  esophageal motility abnormalities compared to cohorts of younger patients.

The purpose of this study is to determine which position, maneuvers, commands, or combination thereof generates the highest pressure at the EGJ as assessed by high-resolution esophageal manometry and thus greater or more robust contraction of the diaphragm.

The goal of this study is to assess long-term outcomes in patients diagnosed with ineffective esophageal motility on high-resolution esophageal manometry including symptoms, treatments, and burden of diagnostic testing and medical evaluation.

The purpose of this study is to assess the effects of restrictive breathing on esophageal function measured by high-resolution esophageal manometry.

The purpose of this study is to assess findings on nailfold video capillaroscopy (NVC) and their association with esophageal dysfunction, specifically esophageal symptoms through self- reported questionnaires and dysmotility assessed by high-resolution manometry (HRM) in patients with concern for systemic sclerosis, which may provide prognostic or diagnostic information using a noninvasive quick and safe procedure.