Genomic Sequencing: Tapestry Study

The Tapestry DNA Sequencing Research Study is designed to understand the short-term and long-term impact of genetic testing on people's health care when their DNA results are part of the electronic health record.

Genetic data from participants will also be used to create a genomic registry meant to support research for many years. By storing the genetic information of many people in one registry, researchers save time because they can skip the step of finding new participants for each new project.

This unique data asset will be available for research applications at Mayo Clinic and with partners. Researchers may request access to this data as they explore how to prevent, screen or treat disease.

Strict policies and procedures are in place to protect data privacy and use.

The goal of the Tapestry study is to provide:

  • An immediate interpretation of ancestry, genealogy and several nondisease traits, as well as clinically actionable variants for an inherited form of high cholesterol called familial hypercholesterolemia (FH), hereditary breast and ovarian cancer (HBOC), and Lynch syndrome — a form of hereditary colorectal cancer — to each participant
  • An additional subset of focused clinically actionable genetic findings — such as certain types of hereditary cancers, hereditary heart conditions and severe responses to certain medications — to be returned to the provider and to the participant via the provider, genetic counselor consultation, or Mayo Clinic research interpretation
  • Stored genomic and phenotypic data for future research analysis


You may be able to participate in the Tapestry study if you are:

  • 18 years old or older
  • A registered Mayo Clinic patient

You are not eligible to participate in the Tapestry study if you are:

  • A resident of the state of New York
  • A patient with an active blood (hematologic) cancer
  • A recipient of an allogeneic bone marrow transplant

If you do not want the results of this genetic testing to be part of your electronic health record, you should not take part in this study.


Patients and referring physicians can contact the Tapestry study team for more information:

Tapestry DNA Sequencing Research Study

  • Center for Individualized Medicine
  • Mayo Clinic
    200 First St. SW
    Rochester, MN 55905
  • Phone: 507-422-6373
  • Email:

You can also contact the Center for Individualized Medicine for information on clinical studies and trials.