The research laboratory of Andrew D. Badley, M.D., focuses on translating clinical observations by performing basic science experiments to understand the mechanistic basis underlying those observations.

This approach has led the laboratory in many varied and unpredicted directions, including describing two novel molecules:

  • TNF-related apoptosis-inducing ligand (TRAIL)short, an antagonistic TRAIL splice variant
  • Casp8p41, a fragment of caspase-8 that is produced through the action of HIV protease


Dr. Badley's Human Immunodeficiency Virus Lab is affiliated with several Mayo Clinic research areas and training programs:

About Dr. Badley

Andrew D. Badley, M.D., was born in Sydney, Nova Scotia. He earned his B.S. degree in 1985 and an M.D. degree in 1990, both from Dalhousie University in Halifax, Nova Scotia.

After completing residency training in internal medicine in 1994 at Mayo Clinic in Rochester, Minnesota, Dr. Badley completed further training at Mayo Clinic as a clinician investigator trainee in the Division of Infectious Diseases in 1997.

During his training, Dr. Badley received the Dr. J. Geraci Award for Excellence in Infectious Diseases from Mayo Clinic in June 1997, as well as the Young Investigator Award from the Interscience Conference on Antimicrobial Agents and Chemotherapy and American Society for Microbiology (ICAAC/ASM) in September 1997.

Dr. Badley joined the staff of Ottawa Hospital in Ottawa, Ontario, in 1997 as assistant professor in the Division of Infectious Diseases and in 2002 was promoted to an associate professor.

In 2002, Dr. Badley returned to Mayo Clinic in Rochester as a consultant in the Division of Infectious Diseases and brought with him his successful research program. At Mayo Clinic, Dr. Badley is currently the chair of the Department of Molecular Medicine; a consultant in the Division of Infectious Diseases; associate director of the Research Resources component of the Center for Translational Science Activities; and theme leader for infectious disease research on the Research Development Council, an internal Mayo committee.