Rochester, Minnesota


Badley.Andrew@mayo.edu Clinical Profile


Andrew D. Badley, M.D., an infectious disease specialist, is an experienced physician-scientist and entrepreneur whose research focuses on novel therapeutic development, especially in the small-molecule, biologic, cellular and gene therapy space. Dr. Badley has deep experience in preclinical evaluation and prioritization, defining go or no-go experiments and pivotal studies. At Mayo Clinic, Dr. Badley serves as director of the Human Immunodeficiency Virus Laboratory, and is chair of both the Department of Molecular Medicine and the SARS-CoV-2 COVID-19 Task Force.

Dr. Badley has been the recipient of funding from the National Institutes of Health for more than 20 years. He is a frequent public speaker and serves as an adviser to government agencies. Dr. Badley also engages in active, hands-on partnering with other scientists and entrepreneurs to help them grow and scale their products.

Focus areas

  • Novel therapeutic approaches to immune-mediated diseases across the spectrum of immuno-oncology and infectious diseases
  • Regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and the impact of a novel splice variant of TRAIL called TRAILshort on TRAIL signaling
  • Early-stage and pivotal clinical trials of novel therapies for human immunodeficiency virus (HIV) infection and COVID-19

Significance to patient care

Dr. Badley's long-term research goals are to develop novel strategies to cure HIV infection by eradicating HIV reservoirs and to create novel immune-based therapies with applications in both virology and oncology.

Professional highlights

  • 2020 Person of the Year, Twin Cities Business magazine
  • HH Sheikh Khalifa Bin Zayed Al Nahyan Professor of Infectious Diseases Honoring Walter R. Wilson, M.D., Mayo Clinic, 2018
  • Outstanding Investigator Award, Mayo Clinic, 2016
  • Clinician Investigator, Scientist, Mayo Clinic, 2010
  • Fellow, Infectious Diseases Society of America, 2008
  • Dalhousie Young Alumnus Award, Dalhousie University, 2006
  • Elected member, American Society of Clinical Investigation, 2006
  • Fellow, American College of Physicians, 2005
  • Clinical Scientist Award in Translational Research, Burroughs Wellcome Fund, 2005


Primary Appointment

  1. Consultant, Division of Infectious Diseases, Department of Internal Medicine
  2. Enterprise Chair, Department of Molecular Medicine
  3. Medical Director, Medical-Industry Relations

Joint Appointment

  1. Consultant, Department of Molecular Medicine

Administrative Appointment

  1. Associate Chair of Research, Department of Internal Medicine

Academic Rank

  1. Professor of Medicine
  2. Professor of Molecular Medicine


  1. Resident Infectious Disease, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  2. Trainee - Clinician Investigator Trainee, Infectious Diseases Infectious Disease Fellowship, Mayo Graduate School of Medicine
  3. Resident Internal Medicine Residency, Mayo Graduate School of Medicine
  4. Resident Internal Medicine, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  5. Internship Dalhousie University
  6. MD Dalhousie University
  7. Certificate Dalhousie University
  8. BS Dalhousie University
  9. Other Halifax Grammar School, Halifax, Nova Scotia

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