Cytoskeletal Membrane Dynamics: Mark A. McNiven

Defining the cellular mechanisms of liver and pancreatic cancer and metabolic disease
This pancreatic tumor cell shows the actin cytoskeleton (red) and the epidermal growth factor receptor (EGFR) (green) internalizing excess growth factor receptors, which contribute to unchecked growth.
Pancreatic tumor cells grow and invade during metastasis
The cytoplasm (red) and nuclei (blue) of pancreatic cancer cells are invading through a porous filter in culture.
Cellular organelles essential to regulation of hepatocyte fat metabolism
These cellular organelles — the autophagolysosome (AP-LY), the lipid droplet (LD) and the mitochondria (MITO) — are often in close proximity to each other and work synergistically.
The cellular basis of fatty liver disease: Hepatocytes accumulate lipid droplets when exposed to alcohol
Hepatocytes cultured from rats fed a control diet (left) have far fewer lipid droplets (red) than hepatocytes cultured from rats fed a diet containing alcohol for six weeks (right). DNA/nucleus is in blue.

Defining the cellular mechanisms of liver and pancreatic cancer and metabolic disease