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Defining the cellular mechanisms of liver and pancreatic cancers and metabolic disease
This pancreatic tumor cell shows the actin cytoskeleton (red) and the epidermal growth factor receptor (green) internalizing excess growth factor receptors, which contribute to unchecked growth.
Overview
Mayo Clinic's Membrane Trafficking in Disease Laboratory is headed by three interactive leaders who include Mark A. McNiven, Ph.D., Gina Razidlo, Ph.D., and Hong Cao, M.D. The lab's research is focused on membrane and cytoskeletal interactions that drive dynamic processes, such as vesicle transport and migration that are essential to the health and disease of the pancreas, lung and liver. Disruptions to these dynamic functions can lead to life-threatening diseases such as cancer, steatosis or hepatitis.
Supported by the National Institutes of Health and National Cancer Institute, the lab's research is organized into three distinct but related disease-based focus areas that include:
Affiliations
The Membrane Trafficking in Disease Laboratory is affiliated with other Mayo Clinic research areas.