Overview

Mayo Clinic's Membrane Trafficking in Disease Laboratory is headed by three interactive leaders who include Mark A. McNiven, Ph.D., Gina Razidlo, Ph.D., and Hong Cao, M.D. The lab's research is focused on membrane and cytoskeletal interactions that drive dynamic processes, such as vesicle transport and migration that are essential to the health and disease of the pancreas, lung and liver. Disruptions to these dynamic functions can lead to life-threatening diseases such as cancer, steatosis or hepatitis.

Supported by the National Institutes of Health and National Cancer Institute, the lab's research is organized into three distinct but related disease-based focus areas that include:

• Tumor cell growth and migration.
• Lipid droplet biology as it drives fatty liver and cancer.
• Hepatitis B viral infection.

Affiliations

The Membrane Trafficking in Disease Laboratory is affiliated with other Mayo Clinic research areas.

• Biochemistry and Molecular Biology
• Cell Biology Program
• Center for Biomedical Discovery
• Gastroenterology and Hepatology
• Gastrointestinal Cancer Program
• Mayo Clinic Comprehensive Cancer Center — Research
• Mayo Clinic Hepatobiliary SPORE