About the Lab

The Cellular and Molecular Physiology of Gastrointestinal Disorders Laboratory of Gianrico Farrugia, M.D., at Mayo Clinic studies the regulation of gastrointestinal motility in cells and disease models. The lab translates its discoveries into improved treatment of gastrointestinal motility disorders, including gastroparesis, irritable bowel syndrome (IBS) and chronic constipation.

Research in Dr. Farrugia's lab includes projects on:

Dr. Farrugia's laboratory is an integral part of the Enteric Neuroscience Program at Mayo Clinic and collaborates with investigators at Mayo, across the U.S. and around the world.

At Mayo Clinic, Dr. Farrugia's laboratory works in close collaboration and shares similar goals with the laboratories of Adil E. Bharucha, M.B.B.S., M.D.; Tamas Ordog, M.D.; David R. Linden, Ph.D.; Michael Camilleri, M.D.; Michael J. Ackerman, M.D., Ph.D.; and Karl A. Nath, M.D. Their laboratories collaborate on most projects and have a common interest in ion channels, heme oxygenase and gastrointestinal smooth muscle cells, interstitial cells of Cajal, and enteric nerves.

Research in Dr. Farrugia's lab is funded by multiple long-standing grants from the National Institutes of Health and other foundations.