Infectious Diseases Research

Below are current clinical trials.

271 studies in Infectious Diseases Research
(all studies, either open or closed).

Filter this list of studies by location, status and more.

1. Testing of Real-Time Diagnostic Platform (HPView) for the Detection of High-risk HPV Strains in Urine

   Rochester, Minn.

   The purpose of this study is to test whether our developed real-time HPV detection platform (HPView) performs at a comparable level to the clinical gold-standard.

2. Pathogen Identification in Pediatric Hematopoietic Stem Cell Transplant Patients With Suspected Lower Respiratory Tract Infection

   Rochester, Minn.

   This is a multicenter prospective collection of leftover respiratory tract secretions, paired blood and NP swabs, and clinical circumstances from pediatric HCT patients, followed by next generation genomic sequencing, transcriptome analysis, protein biomarker measurement, and statistical modeling.

3. COVID-19 Remote Monitoring

   Jacksonville, Fla.

   As a part of the COVID-19 pandemic, Mayo Clinic Florida is utilizing remote monitoring technology to monitor non-ICU patients in order to identify patients who will need the ICU and prevent crashing patients on the floor. MCF is using approved InTouch video and Biofourmis remote vital sign monitoring technology, both used by Mayo Clinic in other capacities. This study will not be a study of the efficacy or the accuracy of these devices as they are already incorporated as standard of practice. This study will assess the reduction of on floor crashing patients, quality of care, and satisfaction of providers by using this technology.  

4. A Study to Evaluate the Effectiveness of Vacuum-Assisted Dressings for the Management of Open Chest Wounds

   Jacksonville, Fla.

   The purpose of this study is to evaluate the effectiveness of Vacuum-assisted dressings for treating patients who have open chest wounds by comparing the time-to-closure of such wounds to traditional wound care management.

5. A Study of the Donor Screening Experience and the Outcomes from Fecal Transplant in Patients with C. Difficile Infection

   Scottsdale/Phoenix, Ariz., Rochester, Minn.

   The purpose of this study is to evaluate clinical experience with donor screening for fecal transplant, and to evaluate the outcomes from fecal transplant and understand risk factors for fecal transplant failure and relapse after fecal transplant.

6. Genetic Expression in Osteolysis, Infection, Arthrofibrosis & Metal Reactions in THA & TKA: A Microarray Analysis to Characterize Individual Host Response to the Molecular Mechanisms of Loosening and Arthrofibrosis

   Rochester, Minn.

   This study is being conducted to determine gene and protein expression profiles (i.e. which genes and proteins are turned off and on) of those with a possibility of developing osteolysis, infection, arthrofibrosis or metallosis of their THA/TKA.

7. Laboratory Assay Optimization 2.0

   Rochester, Minn.

   The purpose of this study is to better understand the role of HIV and/or HCV infection and/or SARS-CoV-2 on the immune system and potential ways to eliminate the virus(es).

8. "Less Pain, Less Fuss, Right Now!" and "Make It Count!"- Efforts to Enhance Provider Recommendations for HPV Vaccination

   Rochester, Minn.

   We are testing this hypothesis through three phases for which we have developed three protocols. In this phase, with this protocol, we have two primary aims.

   • Aim 1: To assess acceptability and gather input on the design and content of an as-of-yet undistributed reminder-recall to parents of children 11-12 years of age due for an HPV dose that emphasized the pain-reducing measures and the nurse visits

   • Aim 2: To evaluate the process of distributing the reminder-recalls to parents of children 11-12 years of age due for an HPV dose that emphasized the pain-reducing measures and the nurse visits

9. A Study to Evaluate the Characteristics and Role of Mucosal Microbiome after Treatment of Clostridium-difficile Infection

   Rochester, Minn.

   The purpose of this study is to characterize the mucosal microbiome in patients who have recently been treated for Clostridium-difficile Infection (CDI) in comparison to that of control population to determine the effect of the mucosal associated microbiome on outcome of CDI.
   
    

10. A Study to Evaluate The Negative Predictive Value and Non-irritant Skin Testing Concentrations of Antibiotics

    Jacksonville, Fla.

    The purpose of this study is to accurately determine the negative predictive value of skin testing with antibiotics.