A Study to Evaluate the Effectiveness of Vacuum-Assisted Dressings for the Management of Open Chest Wounds


About this study

The purpose of this study is to evaluate the effectiveness of Vacuum-assisted dressings for treating patients who have open chest wounds by comparing the time-to-closure of such wounds to traditional wound care management.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Is scheduled to undergo surgical intervention as part of the standard care for management of intra-thoracic infection

Exclusion Criteria

  • Patent bronchopleural fistulas
  • Severe respiratory failure requiring mechanical ventilation at the time of first consultation
  • Proven or suspected malignancy in the wound
  • Coagulopathy due to medical or pharmacologic reasons
  • Dependency on anticoagulants or antiplatelet medication due to high risk for adverse events if these medications are stopped for a prolonged period of time
  • Allergy to acrylic products

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Shanda Blackmon, M.D., M.P.H.

Closed for enrollment

Jacksonville, Fla.

Mayo Clinic principal investigator

Mathew Thomas, M.B.B.S., M.D.

Closed for enrollment

More information


Publications are currently not available

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