Infectious Diseases Research

Below are current clinical trials.

222 studies in Infectious Diseases Research
(all studies, either open or closed).

Filter this list of studies by location, status and more.

1. COVID-19 Cytokine Assay

   Rochester, Minn.

   The purpose of this research is to evaluate a clinical assay designed to measure biomarkers that will help us understand COVID-19.

2. A Study to Assess the Safety, Tolerability and Effectiveness of Monoclonal Antibodies to Treat Hospitalized Patients with COVID-19

   Rochester, Minn.

   The purpose of this study is to evaluate the effectiveness, safety, and tolerability of REGN10933+REGN10987 in hospitalized adult patients with COVID-19.

3. COVID-19 Remote Monitoring

   Jacksonville, Fla.

   As a part of the COVID-19 pandemic, Mayo Clinic Florida is utilizing remote monitoring technology to monitor non-ICU patients in order to identify patients who will need the ICU and prevent crashing patients on the floor. MCF is using approved InTouch video and Biofourmis remote vital sign monitoring technology, both used by Mayo Clinic in other capacities. This study will not be a study of the efficacy or the accuracy of these devices as they are already incorporated as standard of practice. This study will assess the reduction of on floor crashing patients, quality of care, and satisfaction of providers by using this technology.  

4. COVID-19 and Acute Renal Failure

   Jacksonville, Fla., Scottsdale/Phoenix, Ariz., Rochester, Minn.

   The primary purpose of this study is to examine 1-year survival and rate of secondary infections in COVID-19 patients with and without acute kidney injury (AKI).

    

    

    

5. Genetic Expression in Osteolysis, Infection, Arthrofibrosis & Metal Reactions in THA & TKA: A Microarray Analysis to Characterize Individual Host Response to the Molecular Mechanisms of Loosening and Arthrofibrosis

   Rochester, Minn.

   This study is being conducted to determine gene and protein expression profiles (i.e. which genes and proteins are turned off and on) of those with a possibility of developing osteolysis, infection, arthrofibrosis or metallosis of their THA/TKA.

6. A Study to Evaluate The Negative Predictive Value and Non-irritant Skin Testing Concentrations of Beta-Lactam Containing Antibiotics Other Than Penicillin

   Jacksonville, Fla.

   The purpose of this study is to accurately determine the negative predictive value of skin testing with beta-lactams containing antibiotics other than penicillin.

    

    

    

    

7. Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection

   Rochester, Minn.

   Does a wound vac dressing prevent wound infection after heart surgery?

8. Dental Prophylaxis for the Prevention of Infective Endocarditis

   Rochester, Minn.

   The purpose of this study is to determine the percentage of patients at moderate risk for infective endocarditis (IE) who are receiving antibiotic prophylaxis post-2007 in Olmsted County, Minnesota.

9. A Study to Evaluate the Characteristics and Role of Mucosal Microbiome after Treatment of Clostridium-difficile Infection

   Rochester, Minn.

   The purpose of this study is to characterize the mucosal microbiome in patients who have recently been treated for Clostridium-difficile Infection (CDI) in comparison to that of control population to determine the effect of the mucosal associated microbiome on outcome of CDI.
   
    

10. A Study for the Use of Hepatitis C Virus Seropositive Donors into Hepatitis C Seronegative Liver Transplant Recipients

    Rochester, Minn., Scottsdale/Phoenix, Ariz., Jacksonville, Fla.

    The purpose of this study is to utilize liver allografts from HCV seropositive donors into 10 HCV seronegative recipients.