Structural Testing and Tissue Analysis Service Line

Structural testing and tissue analysis services at Mayo Clinic focus on the physical materials needed for biomedical research. The Biomaterials Histomorphometry Core gives researchers new insights into bone makeup and structure; the Materials and Structural Testing Core focuses on design, simulation, fabrication and modeling of project materials; and the Histology Core processes, embeds, sections and stains animal tissues for research.

Biomaterials Histomorphometry Core

The Biomaterials Histomorphometry Core helps researchers evaluate complex metabolic bone disorders, assess the effects of skeletally active agents, and evaluate new drugs for osteoporosis and other metabolic bone diseases. The core's range of services allows researchers to assess bone formation, mineralization and turnover using the most definitive methods available. Services include:

  • Plastic and paraffin embedding
  • Processing and evaluation of tissues from humans and large and small animals
  • Characterizing biomaterials
  • MicroCT scanning

Read more about the Biomaterials Histomorphometry Core.

Biomechanics Core

The Biomechanics Core provides services including:

  • Mechanical testing
  • Simulation
  • Data analysis
  • Engineering design
  • Fabrication
  • Simulation
  • Modeling

Services are applied to projects in a broad range of specialties, including dentistry, cardiology, gastroenterology, obstetrics and gynecology, and orthopedics. Services help researchers evaluate clinical interventions on skeletal joints and tissue structures, simulate medical device performance to treat the effects of degenerative disease and injury, and characterize the mechanical properties of biomedical materials.

Read more about the Biomechanics Core.

Histology Core

Located at Mayo's campus in Phoenix/Scottsdale, Arizona, the Histology Core Facility specializes in processing, embedding, sectioning and staining of animal tissues. The core offers standard H&E staining, a variety of standard special stains, and veterinary pathology support that includes teleconference and videoconference for slide review.

Read more about the Histology Core.