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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-6 of 6 for Spinal cord injury

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Mobility and Therapeutic Benefits Resulting from Exoskeleton Use in a Clinical Setting

    Rochester, MN

  2. Riluzole in Spinal Cord Injury Study

    Rochester, MN

  3. A Study to Evaluate Cardiovascular Effects of High Intensity Interval Training in Individuals with Paraplegia

    Rochester, MN

  4. A Study of Transcutaneous and Epidural Spinal Stimulation for Enabling Motor Function in Humans with Motor Complete Paraplegia

    Rochester, MN

  5. Spinal Cord Injury and Dysfunction Registry: Acute Injury Through Life Long Care

    Rochester, MN

  6. Spinal Cord Injury Rehabilitation Research Registry

    Rochester, MN

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