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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 15 for Parkinson's disease

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate the Safety and Effectiveness of VY-AADC02 in Advanced Parkinson's Disease with Motor Fluctuations

    Jacksonville, FL

  2. A Study to Establish a Registry of Deep Brain Stimulation with the VERCISE™ System

    Jacksonville, FL

  3. A Phase 3 Study With P2B001 in Subjects With Early Parkinson's

    Scottsdale/Phoenix, AZ

  4. A Study to Evaluate TD-9855 to Treat Symptomatic Neurogenic Orthostatic Hypotension (snOH) in Subjects with Primary Autonomic Failure

    Rochester, MN

  5. A Study to Evaluate the Durability of TD-9855 for Treating Symptomatic Neurogenic Orthostatic Hypotension in Subjects with Primary Autonomic Failure

    Rochester, MN

  6. A Clinical Study of NLY01 in Patient's With Early Parkinson's Disease

    Jacksonville, FL

  7. A Study to Evaluate Zoledronic Acid for Fracture Prevention in Parkinson's Disease Patients

    Rochester, MN

  8. A Study to Evaluate the Effectiveness, Safety, and Tolerability of NLY01 in Early-stage Parkinson's Disease

    Scottsdale/Phoenix, AZ

  9. A Study to Evaluate Quantitative Phenotypes of Movement Disorders

    Jacksonville, FL

  10. A Study of Biofluids in Parkinson Disease and Related Disorders

    Rochester, MN

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