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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 18 for Alzheimer's disease

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  • Study status: Open/Status Unknown
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  1. A Long Term Study of Molecular and Structural Imaging in Atypical Alzheimer's Disease

    Rochester, MN

  2. A Study to Evaluate the Safety and Effectiveness of Gantenerumab in Participants With Early Alzheimer's Disease (AD)

    Scottsdale/Phoenix, AZ

  3. A Study Evaluating the Use of 48-hour Ambulatory EEG Monitoring in Early Onset Alzheimer’s Disease

    Jacksonville, FL

  4. Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss

    Jacksonville, FL, Rochester, MN

  5. A Study to Collect Blood DNA Samples from Patients with Clinically Diagnosed Alzheimers Disease, Lewy Body Disease, and Frontotemporal Degeneration

    Rochester, MN

  6. A Study to Evaluate Alzheimer Disease Biomarkers in Cerebrospinal Fluid (CSF)

    Rochester, MN

  7. A Study to Assess Educational Needs and Perceived Barriers to Care Among Individuals with Chronic Health Conditions and Their Caregivers

    Jacksonville, FL, Rochester, MN

  8. Magnetic Resonance Elastography of Dementia

    Rochester, MN

  9. Advanced Care Planning in Dementia

    Jacksonville, FL

  10. Partnership for Early Detection of Alzheimer's Disease Using Advanced MR Technology

    Rochester, MN

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