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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-19 of 19 for Alzheimer's disease

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  • Study status: Open/Status Unknown
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  1. A Study to Develop A Family Registry to Collect Alzheimer's Biomarkers

    Jacksonville, FL

  2. A Study to Evaluate Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease

    Rochester, MN

  3. Mayo Alzheimer's Disease Research Center

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. Cerebrospinal Fluid (CSF) Biomarkers for Prediction of Dementia

    Jacksonville, FL, Rochester, MN

  5. A study to create and analyze a comprehensive longitudinal resource using testing results from those with genetic risk of Alzheimer's disease

    Scottsdale/Phoenix, AZ

  6. A Study of Early-onset Alzheimer's Disease

    Jacksonville, FL, Rochester, MN

  7. A Study of the Brain & Body Donation Program

    Scottsdale/Phoenix, AZ

  8. TRC-PAD Program: In-Clinic Trial-Ready Cohort

    Rochester, MN, Jacksonville, FL

  9. A Study to Evaluate MR of CSF Dynamics

    Rochester, MN

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