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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 19 for Cardiomyopathy

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  • Study status: Open/Status Unknown
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  1. A Study of Oxygen Cost of Exercise in Patients with and without Heart Failure

    Rochester, MN

  2. A Study to Evaluate the Effectiveness and Safety of G10 in Subjects with Transthyretin Amyloid Cardiomyopathy

    Rochester, MN

  3. An Extension Study of Mavacamten in Adults with Hypertrophic Cardiomyopathy Who Have Completed the MAVERICK-HCM (MYK-461-006) or EXPLORER-HCM (MYK-461-005) Trials (MAVA-LTE)

    Scottsdale/Phoenix, AZ

  4. Prospective Assessment of Premature Ventricular Contractions Suppression in Cardiomyopathy(PAPS)

    Rochester, MN

  5. A Study to Evaluate AuTophagy Activation for Cardiomyopathy Due to Anthracycline Treatment

    Rochester, MN

  6. A Study to Evaluate the Effectiveness and Safety of Vutrisiran in Patients with Transthyretin Amyloidosis with Cardiomyopathy (ATTR Amyloidosis with Cardiomyopathy

    Rochester, MN

  7. A Study to Evaluate Long-term Outcomes of Alcohol Septal Ablation for Hypertrophic Cardiomyopathy

    Rochester, MN

  8. Identification of Novel Genetic Variants and Biomarkers of Disease Progression in Arrhythmogenic Cardiomyopathy

    Rochester, MN

  9. A Study of Biomarkers to Predict Cancer Therapy-related Cardiotoxicity

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. Electrogram-Guided Myocardial Advanced Phenotyping (The eMAP Trial)

    Rochester, MN

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