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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-18 of 18 for Cardiomyopathy

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  • Study status: Open/Status Unknown
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  1. A Study of the Effect of Myectomy on the Sudden Cardiac Death Risk in Hypertrophic Cardiomyopathy

    Rochester, MN

  2. A Study to Evaluate Cardiopulmonary Exercise Testing in Liver Transplant Candidates

    Scottsdale/Phoenix, AZ

  3. A Study of the Impact of Cardiac Rehabilitation after Myectomy Procedure for Hypertrophic Cardiomyopathy

    Rochester, MN

  4. A Study to Assess Measurements in Cardiomyopathy Patients Using Software for Multi-level Reconstruction of Three Dimensional Transesophageal Echocardiography (3DTEEI Images

    Rochester, MN

  5. Analysis of Outcomes of Left Cardiac Sympathetic Denervation in Arrhythmia Syndromes and Cardiomyopathies

    Rochester, MN

  6. Patient-Specific Induced Pluripotent Stem Cell Models for Heritable Channelopathies and Cardiomyopathies

    Rochester, MN

  7. A Study to Determine the Incidence of Atrial and Ventricular Arrhythmias in Patients with Hypertrophic Cardiomyopathy

    Rochester, MN

  8. Accelerated Stem Cell Senescence in Heart Failure

    Rochester, MN

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