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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 60 for

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  1. A Study of Lutetium Lu 177 Dotatate (Lutathera®) in Patients with Inoperable, Progressive Meningioma after External Beam Radiation Therapy

    Rochester, MN

  2. Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

    Rochester, MN

  3. Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Stage IV Non-Small Cell Lung Cancer Patients Who Are PD-L1 Negative

    Scottsdale/Phoenix, AZ, Jacksonville, FL, La Crosse, WI, Rochester, MN

  4. A Study to Evaluate Contouring Organs at Risk for Treatment Planning

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. A Study to Compare Optimal MRI Timing for Pre-surgical Planning to LINAC-based Therapy

    Rochester, MN

  6. A Study to Evaluate Fractionated Radiation Therapy Utilizing GRID Therapy for Locally-advanced Bulky Tumors

    Rochester, MN, Jacksonville, FL

  7. A Study to Evaluate the Adaptive Image Receive (AIR) Coil System for Patients Undergoing MR Imaging Simulation

    Rochester, MN

  8. A Study to Evaluate Circulating Tumor DNA (ctDNA) and Immunophenotyping as Potential Biomarkers in Patients Undergoing Regional Nodal Irradiation for Breast Cancer

    Rochester, MN

  9. Fertility Outcomes in Lymphoma Patients

    Jacksonville, FL

  10. Short-course Radiation Therapy for Hepatocellular Carcinoma

    Scottsdale/Phoenix, AZ, Rochester, MN

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