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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 39 for

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  1. Study of Pembrolizumab (MK-3475) vs Standard Therapy in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (MK-3475-177/KEYNOTE-177)

    Scottsdale/Phoenix, AZ, Rochester, MN, Rochester, MN

  2. A Study to Evaluate Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy for HER2+ Gastrointestinal Cancers

    Scottsdale/Phoenix, AZ, Rochester, MN

  3. A Study to Evaluate Encorafenib Plus Cetuximab with/without Chemotherapy to Treat Metastatic Colorectal Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. A Phase 1b/2 Study of Onvansertib (PCM-075) in Combination with FOLFIRI and Bevacizumab for Second-Line Treatment of Metastatic Colorectal Cancer in Patients with a KRAS Mutation

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. "Prescribing" Exercise to Cancer Patients at High-Risk for Falls

    Rochester, MN

  6. A Study Evaluating the Safety and Effectiveness of Therapies in Patients with Metastatic Colorectal Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. A Study of Intravital Microscopy (IVM) in Human Solid Tumors

    Jacksonville, FL

  8. A2B101-101: Obtaining Primary Solid Tumor Tissue from Subjects Having Primary Surgical Resection for Certain Tumor Types and Leukapheresis for CAR T-cell Therapy Manufacturing

    Rochester, MN, Jacksonville, FL

  9. A Study to Evaluate Colorectal Polyps with Dietary Inflammation During Colonoscopy

    Jacksonville, FL

  10. Surveillance of Colorectal Dysplasia to Treat Inflammatory Bowel Disease with Wide Area Transepithelial Sample (WATS)

    Rochester, MN

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