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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 42 for Colon cancer

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  1. A Study of a Personalized Cancer Vaccine Targeting Shared Neoantigens

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. A Phase 1b/2 Study of Onvansertib (PCM-075) in Combination with FOLFIRI and Bevacizumab for Second-Line Treatment of Metastatic Colorectal Cancer in Patients with a KRAS Mutation

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. A Study of a Personalized Neoantigen Cancer Vaccine

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. A Study to Evaluate the Challenges, Behavioral Patterns, and Preferences of Minority Patient Participation in Clinical Trials

    Jacksonville, FL, Scottsdale/Phoenix, AZ, Rochester, MN

  5. A Study of Intravital Microscopy (IVM) in Human Solid Tumors

    Jacksonville, FL

  6. A Study to Evaluate Colorectal Polyps with Dietary Inflammation During Colonoscopy

    Jacksonville, FL

  7. Time Longitudinal Study of the Microbiome in Colorectal Cancer Subjects

    Rochester, MN

  8. A Study to Develop a Biorepository of Blood Samples from Cancer Patients Participating in the Gemini (IRB 19-006717) Protocol

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  9. A Study to Assess a New Personalized Tool for Colorectal Cancer Peritoneal Disease Treatment

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. A Bio-bank for Patients with Inflammatory Bowel Disease Associated Neoplasia

    Rochester, MN

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