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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 42 for Colon cancer

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  • Study status: Open/Status Unknown
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  1. A Study of ASP1948 in Subjects with Advanced Solid Tumors

    Scottsdale/Phoenix, AZ

  2. Study of TBio-6517, Given Intratumorally, Alone or in Combination With Pembrolizumab, in Solid Tumors

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  3. Tucatinib and Trastuzumab for Patients with HER2-positive Metastatic Colorectal Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN

  4. A Study to Evaluate Precision Pharmacogenomics in Cancer Patients

    Scottsdale/Phoenix, AZ

  5. A Study of MEDI5395 in Combination With Durvalumab in Subjects with Select Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Rochester, MN

  6. A Study to Determine the Feasibility of Transanal Robot-assisted Resection of Distal Colorectal Lesions Using the Medrobotics Flex® System

    Rochester, MN

  7. A Study to Investigate the da Vinci SP® Surgical System in Colorectal Procedures for Benign and Malignant Disease

    Rochester, MN

  8. A Study to Evaluate Duloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal Cancer

    Rochester, MN, Mankato, MN, Eau Claire, WI

  9. Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

    Albert Lea, MN, Eau Claire, WI, Mankato, MN, Jacksonville, FL, Rochester, MN, La Crosse, WI

  10. Gemini Study to Evaluate the Integration of Cancer Genetic Testing into a Cancer Clinical Practice at Mayo Clinic at Arizona

    Scottsdale/Phoenix, AZ, Jacksonville, FL

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