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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 81-90 of 102 for Breast cancer

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  • Study status: Open/Status Unknown
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  1. Comparison of Molecular Breast Imaging and Digital Breast Tomosynthesis for Screening in Women With Dense Breasts

    Rochester, MN, La Crosse, WI

  2. Viscoelastic Parameters Estimation and Imaging for the Assessment of Axillary Lymph Nodes

    Rochester, MN

  3. A Study to Assess Pre-analytical Factors Affecting ctDNA Analysis in Early and Locally-advanced Breast Cancer

    Scottsdale/Phoenix, AZ

  4. Breast Cancer: Can We Predict Pathological Complete Response following Neoadjuvant Treatment?

    Scottsdale/Phoenix, AZ

  5. Genetic Analysis in Blood and Tumor Samples From Patients With Advanced or Metastatic Estrogen Receptor Positive and HER2 Negative Breast Cancer Receiving Palbociclib and Endocrine Therapy

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. A Study to Quantify Microvasculature Imaging for Breast Cancer Detection and Monitoring

    Rochester, MN

  7. A Study to Develop a Cohort Database and Study Platform in Breast Cancer Survivors Using Multiscale Omics

    Rochester, MN

  8. A Study to Evaluate the Safety of the Goldilocks Procedure with Implant-Based Reconstruction

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. A Study to Analyze Symptoms and Quality of Life Issues in Women Living with Metastatic Breast Cancer

    Jacksonville, FL

  10. GENetic Risk Estimation of Breast Cancer Prior to Decisions on Preventive Therapy Uptake, Risk Reducing Surgery or Intensive Imaging Surveillance

    Albert Lea, MN, Austin, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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