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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 71-80 of 107 for Breast cancer

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate the Safety of Lasofoxifene in Combination with Abemaciclib in Advanced or Metastatic ER+/HER2− Breast Cancer with ESR1 Mutation

    Jacksonville, FL

  2. Study of AVB-620 in Women With Primary, Nonrecurrent Breast Cancer Undergoing Surgery

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. A Study to Evaluate Left and Right Ventricular Function in Relation to Exercise Capacity in Breast Cancer Survivors

    Jacksonville, FL

  4. A Study to Evaluate Factors in Breast Cancer Screening Among Asian Americans in Olmsted and Surrounding Counties

    Rochester, MN

  5. A Study of Benign Breast Tissue and Disease, and Breast Cancer Development

    Jacksonville, FL

  6. A Study of Vulvovaginal Symptoms in Premenopausal Stage 0-III Breast Cancer Patients Treated on Aromatase Inhibitors and Ovarian Suppression

    Jacksonville, FL

  7. A Study to Analyze the Prevalence of Depression and Anxiety in Newly-diagnosed Breast Cancer Patients in a Community Hospital

    La Crosse, WI, Albert Lea, MN, Austin, MN, Eau Claire, WI, Rochester, MN

  8. Lobular Involution-Based Response to Antiendocrine Therapy for Women with Breast Atypical Hyperplasia

    Jacksonville, FL

  9. A Study of Women undergoing Mammogram Screening at Mountain Park Clinic

    Scottsdale/Phoenix, AZ, Rochester, MN

  10. A Registry for the Collection and Maintenance of Biological Specimens for Breast Cancer Research

    Rochester, MN

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